1) Developing a new service delivery model that is more affordable for the public sector; 2) Determine a best-fit service delivery model; 3) Deliver a quality, customer focussed service; 4) Align resources, support services and infrastructural development for service delivery; 5) Become laboratory services "Employer of Choice"; 6) Prioritise innovation and research to be relevant, appropriate and leading edge; 7) Become the health information powerhouse; 8) Drive stakeholder collaboration; 9) Position NHLS as the "Provider of Choice" for National Health Insurance (NHI); and 10) Protect the community and environment.