Mankweng served as primary hospital for its surrounding community. The hospital also served as the secondary hospital for Capricorn District. The hospital had tertiary services for Limpopo province in certain clinical areas. It participated in 15 out of 50 recognised tertiary services. A number of specialist's clinical departments existed at the Mankweng Hospital. These range from - Anaesthesiology; Paediatrics and Child Health; Neonatal ICU; Internal Medicine; Family Medicine; Phela O'Phedishe (ARV Clinic); Clinical Forensic Medicine; Clinical Psychology; General Surgery; Trauma Surgery; Psychiatry: Adult and Paediatric; Orthopaedics and Prosthondotics; Clinical Support Services; Optometry; Occupational Therapy; Physiotherapy; Clinical Social Work; Oral Health; Radiography; Speech and Audiology; Pharmacy; Dietetics; Clinical Engineering; Laboratory Services; and Blood Bank.